Oven Preparation: Preheat the oven to a temperature of 375ºF. Thoroughly grease 12 standard-sized muffin cups using non-stick cooking spray. Set this aside for subsequent use.
Dough Preparation: Carefully extract the dough from its canister, ensuring to seal any seams present. Gently stretch and shape the dough into a rectangle measuring approximately 8x18 inches. Using a sharp knife, section the dough into 12 even squares. Proceed to fit these squares into the previously prepared muffin cups, ensuring a snug fit.
Cheese Mixture: In a medium-sized mixing bowl, combine the softened cream cheese, Italian seasoning, and half of the mozzarella cheese. Stir until the mixture is uniform in consistency.
Assembly: Equally divide the cream cheese mixture, placing a portion into the base of each muffin cup. On top of this, position a meatball. Follow this by spooning approximately 2 tablespoons of spaghetti sauce over each meatball. To finish, evenly distribute the remaining mozzarella cheese over each cup.
Baking: Place the muffin tray into the preheated oven and allow the Meatball Sub Cupcakes to bake for a duration of 15 to 18 minutes, or until they attain a deep golden brown hue. Once done, remove from the oven and allow them to cool slightly before serving.